Clinical Rationale for GLP-1RAs in T2DM It is well recognised that T2DM is a complex and multifactorial disorder attributable to the eight underlying pathophysiological defects labelled the ominous octet [7]
91 In UC patients, endoplasmic reticulum function may be impaired, leading to abnormal accumulation of intracellular proteins and exacerbation of the cellular inflammatory response
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Within this database, they identified 638,501 individuals with a prior occurrence of acute pancreatitis
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