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Alternative therapy, such as hydroxocobalamin, is advised
It binds to GLP-1 receptors in the hypothalamus and brainstem, reduces appetite, slows gastric emptying and enhances the feeling of fullness
It also plays a crucial role in insulin levels and blood sugar control
Physicians Committee for Responsible Medicine
However, the US prescribing information states that the possible role of phentermine cannot be fully ruled out, and rare cases of valvular heart disease have been reported in people who reportedly took phentermine alone