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Semaglutide reduces appetite, but on its own, it does not directly increase energy output

It appears in human plasma at approximately 200 ng/ml in young subjects, with a drop of more than 60 % between ages 20 and 60, an observation that motivated forty years of research on its role in tissue repair, wound healing, hair growth and cutaneous longevity

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Its primary biological directive is to protect delicate cellular architecture, including mitochondrial DNA and cell membranes, from the destructive forces of oxidative stress

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