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The expression for each gene was determined as the relative expression of the housekeeping gene -actin
It found that the risk of alopecia for people taking GLP-1s was 37% higher than for people taking SGLT-2 inhibitors, and 68% higher than for those taking DPP-4 inhibitors
A phase II trial focusing on individuals with overweight or obesity, coupled with hypertension or dyslipidemia but without T2D, found that cagrilintide (2.4 mg) alongside diet and exercise, led to a 10% body weight reduction compared to 3% with placebo over 26 weeks [99]
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