scientists, however, cautioned that long-term, continuous exposure to epitalon could be carcinogenic
The difference isn't subtle
The role of dose, timing and adherence Dose is the simplest factor to look at first
FIGURE 14 The available structural data on the GLP-1GLP-1R system reveal that GLP-1 occupies the deep transmembrane pocket of the GLP-1R and establishes several intermolecular interactions with crucial residues on the N-terminus, ECL2, TM1, TM2, TM5, TM6, and TM7 of GLP-1R (Figure 14), which are also sustained over the duration of MD simulations
doi: 10.1038/s41580-018-0092-0 15
The ability of alpha-lipoic acid and other nutrients to trigger production and increase levels of GSH