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Body composition analyses using dual-energy X-ray absorptiometry (DEXA) scans revealed that a majority of the weight lost was fat mass
In this combined analysis, we observe that the degree of BMI loss depends strongly on sex, drug type, time on treatment and drug dosage, consistent with previous reports 11 , and has a relatively weak dependence on pre-treatment BMI (with higher starting BMI associated with greater BMI loss)
In people with metabolic liver disease, the same weekly dosing showed dramatic reductions in liver fat , suggesting not just weight-loss but also meaningful improvements in liver health
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