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It is always important to remember potential causes of drug induced B12 deficiency
It was tested on healthy volunteers and on a small cohort of patients with Crohns disease
The lack of comprehensive human trials means potential dangers and interactions with other medications remain uncertain
Animal studies have not reported major toxicity, but the lack of comprehensive human data means risks are unknown467
In a meta-analysis of 14 studies of gastrectomy for gastric cancer, including collectively 2627 subjects, the prevalence of vitamin B12 deficiency surgery was 49% (26)
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