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A planned part of the Phase 2 obesity trial looked at 98 participants who also had metabolic dysfunction-associated steatotic liver disease (MASLD, the condition formerly called non-alcoholic fatty liver disease)
Metformin has been found to produce a more significant degree of weight loss in patients with polycystic ovary syndrome (PCOS), a complex endocrine disorder with symptoms including diabetes, obesity, infertility and heart disease (Li et al, 2021)
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But as science continues to confirm its broad-spectrum effects, from blood sugar regulation to cancer prevention, it may well deserve its place at the top of the longevity pyramid
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Krijt J, Vackova M, Kozich V (2001)
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