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doi: 10.1016/S0140-6736(04)17025-6 106 HanselTTKharitonovSADonnellyLEErinEMCurrieMGMooreWMet al

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First, the hyperacetylation of the mitochondrial malate-aspartate shuttle protein inhibits the oxidation and transport of NADH in the mitochondria, resulting in an imbalance of redox in the cytoplasm

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