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Treatment of newborn rats with L-buthionine sulfoximine (BSO), an irreversible inhibitor of GCLC, leads to hepatic abnormalities including mitochondrial dysfunction 10
Body composition
Treatment of early ring-stage artemisinin resistant (Cam3.II R539T ) and sensitive (Cam3.II REV ) parasites with 10 mM of BSO for 1 h significantly depleted both -Glu-Cys and reduced GSH levels in both lines compared to untreated controls (Fig 5A)
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