The excess AGEs could lead to non-enzymatic cross-linking of collagen, break the adhesion of osteoblasts to the extracellular matrix and leads to bone fragility (Mohsin et al., 2019)
& Nicholls, S.J
Despite these apparent advantages, most of the research has been conducted on ALA because it is more widely available and has simply been around as a supplement for longer
There has now been individual publication of pooled safety data for the three available DPP-4 inhibitors
In a survey of 436 participants with T1D, 72% of those who drive a vehicle reported having hypoglycemia events while driving, and 4.3% reported having a vehicular accident due to hypoglycemia in the previous 2 years (66)
Try to include those high in omega-3 fatty acids, like salmon, walnuts, and chia seeds, for their anti-inflammatory benefits