These changes in gene expression are dependent on the time interval during which the genes were analyzed, as well as the type of vessel investigated
General inflammation and slow healing This is the broad bucket, and honestly it is the one most likely to lead to disappointment if expectations are not managed
PMC 1222196
The peptide sequence, alanine-histidine-lysine bound to copper, was chosen because of how it interacts with growth factor receptors and anti-apoptotic pathways
What Published Mechanism Research Implies (And Doesn't) GHK-Cu's documented activities stimulating fibroblast proliferation, modulating collagen and glycosaminoglycan synthesis, affecting gene expression at scale (Pickart & Margolina describe an effect on roughly 31% of human genes, PMID 29986520) are mechanism findings, not adverse-event predictions
As with any therapeutic compound, application under physician guidance is recommended to ensure appropriate concentration and formulation