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3d), as did treatment with other TS-targeted antifolates pemetrexed and methotrexate in colon (Extended Data Fig

Safdie 2012)

Pharmaceutical Strategies for the Topical Dermal Delivery of Peptides/Proteins for Cosmetic and Therapeutic Applications

A trial examining 40 women aged 40 to 65 demonstrated that topical GHK-Cu applied twice daily for 8 weeks reduced wrinkle volume by 55.8% and wrinkle depth by 32.8%