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Long term treatment with metformin in patients with type 2 diabetes and risk of vitamin B-12 deficiency: Randomised placebo controlled trial

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433 Maintaining urate levels at or below 360 mol/L through urate-lowering therapy is deemed safe and crucial for the prevention and reversal of joint, cardiovascular and renal damages

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The presence of L-Carnitine and Co-Enzyme Q10 supports natural cellular energy production, which may help maintain energy and reduce tiredness