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Considerations for Oral Administration Avoids needles and injection-site reactions Convenient to take and to travel with Considerations for Injectable Administration Higher bioavailability than most oral routes More consistent blood levels Faster onset of action Not sure which approach is appropriate for you

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Tolerability, safety and pharmacodynamics of oral, small-molecule glucagon-like peptide-1 receptor agonist danuglipron for type 2 diabetes: a 12-week, randomized, placebo-controlled, phase 2 study comparing different dose-escalation schemes

If your nausea is more severe or doesnt seem to be improving, talk to your healthcare provider to see if you need to adjust your dose.

But retatrutide adds a third target: the glucagon receptor

This will help you avoid infections