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This post was updated in October 2024 to reflect the latest regulatory news.
When activated, GLP-1 receptors trigger a cascade of metabolic effects including enhanced insulin secretion, reduced glucagon release, delayed gastric emptying, and appetite suppression through direct action on brain centers
It may be difficult to get a countervailing narrative across on Hubermans home turf, as Hill himself acknowledges, but he thinks its crucial to try
That is why they work better together than alone
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Metformin can cross BBB and accumulate in some brain regions affecting various CNS functions by inhibiting neuronal apoptosis with promoting the neurogenesis process by activation of neuronal protein kinase C (PKC)
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