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From these observations, it is reasonable to speculate that the enhancing effects of other PAMPs on NHO described herein, may also be mediated by enhanced secretion of IL-1 and OSM by activated macrophages

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Furthermore, it has been found that more than 3.6 105 ha of carbonate rock area is contaminated with heavy metals associated with coal-fired zinc smelting activities under geochemical anomalies with high heavy metal backgrounds in northwest Guizhou Province [2]