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In the Phase 2 retatrutide trial ( Jastreboff et al., NEJM 2023 ), body-composition imaging showed fat mass falling substantially more than lean mass, meaning the majority of the weight lost was fat
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For keeping up the treatment, injections are often given monthly
The Competition: How Other Fat Loss Peptides Compare Giving Retatrutide a fair assessment means looking squarely at what else is available and what the evidence says about each option
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