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Improved mitochondrial efficiency has been observed, but prolonged caloric restriction may reduce mitochondrial biogenesis and oxidative capacity, compromising muscle function even if absolute mass loss is modest [35]
But a technique comes of age when it finds its o w n repertoire of messages
Han, H.S
Activated microglia drive the immune response to the inflammatory state releasing immune signaling molecules (cytokines, and chemokines), and inducing neuronal cell death ( These data underline the importance of optimal glycemic control and call for major pharmacological interventions to reduce the risk of cardiometabolic-related cognitive impairment
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