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Sci Transl Med 5:209ra151
We will examine the role of DPP-4 inhibitors in clinical practice Pharmacology In humans, two incretin peptide hormones have been identified
Excessive ROS triggers oxidative stress Although ROS production in mitochondria is in balance with an intracellular antioxidant system under physiological conditions, the balance is easy to be disrupted under pathological conditions, such as radiation, hypoxia, cytokines, hyperlipidemia, and hyperglycemia, which results in the accumulation of ROS, facilitating oxidative stress, cell damage, and diseases, such as cancer, cardiovascular disease, neurological disease, respiratory disease, and so on
Eric Topol: [00:24:48] And we should be taking out the ones that are really, unequivocally linked to promoting inflammation
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