Penetration through the skin barrier is limited, particularly for larger molecules, and results depend heavily on the delivery vehicle and formulation
Still, high doses could have some side effects, like dizziness, headache, anxiety, nausea, and vomiting
Isoliquiritin apioside relieves intestinal ischemia/reperfusion-induced acute lung injury by blocking Hif-1-mediated ferroptosis
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In addition, malignant serous ovarian tissue samples showed significantly higher reactive carbonyl contents compared with non-diseased controls (p = 0.009), while GPX3 levels were markedly decreased in serous cystadenoma and malignant tissue samples, as well as in non-diseased controls, compared with borderline tumors