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Per CMS Article A54880, which governs NOC drug documentation requirements, every J3490 claim must include the following on the claim line and in supporting records

This hormone allows the body to metabolize fat and use it as energy for both mother and fetus

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It's important to note that these medications carry a boxed warning for risk of thyroid C-cell tumors and are contraindicated in patients with a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN2)

Oral Wegovy (semaglutide 25 mg daily) produced 16.6% weight loss at 64 weeks in the OASIS 4 trial