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In addition to regulating appetite, the semaglutide also affects insulin secretion, blood glucose homeostasis, energy expenditure, and lipid metabolism processes, as well as serum metabolism

If youve been treated for hypothyroidism and still feel symptomatic despite normal TSH, a full thyroid panel and a conversation with an endocrinologist is worth pursuing before or alongside GLP-1 treatment

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Mar 19, 2026, 12:04 ET Average weight loss of ~21% at 72 weeks in adults with obesity if all patients stayed on treatment * with Wegovy HD (~19% regardless of whether patients stayed on treatment ** ) in the STEP UP trial 1 In the STEP UP trial, about one in three trial participants taking Wegovy HD achieved 25% weight loss or higher 1 This approval for Wegovy further expands its already robust label inclusive of multiple formulations, including Wegovy pill, and indications not available with other GLP-1 weight loss medicines PLAINSBORO, N.J., March 19, 2026 /PRNewswire/ -- Novo Nordisk today announced US Food and Drug Administration (FDA) approval of a new higher dose of Wegovy , Wegovy HD (semaglutide) injection 7.2 mg, which demonstrated substantial weight loss in adults with obesity in the STEP UP trial