Here is what the evidence actually says, including the parts that require clinical judgment
(2009) Therapeutic efficacy of ipilimumab, an anti-CTLA-4 monoclonal antibody, in patients with metastatic melanoma unresponsive to prior systemic treatments: clinical and immunological evidence from three patient cases
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When the amount of tyrosinase is reduced, the melanin formation process is also prevented, leading to brighter skin and less darkening
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Occipital cortex There were three studies using data from the occipital cortex including 67 patients (mean age of 26.3, 46.2% male) and 48 healthy volunteers (mean age of 27.2, 41.7% male) (Freed et al