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No dose-ranging studies have established safety margins, optimal administration routes, or duration of treatment
Taken together, these findings suggest that by supporting fibroblast function and extracellular matrix assembly, BPC-157 may contribute to the formation of a more orderly collagen network during ligament and tendon repair
BPC 157 entered early-phase clinical development for inflammatory bowel disease as PL 14736 (Pliva, Croatia), and a 2025 pilot examined intravenous administration in a small cohort, but no adequately powered randomised controlled trial exists
