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The FDA has approved these agents for chronic weight management in adults with obesity (BMI 30 kg/m) or overweight (BMI 27 kg/m) with at least one weight-related comorbidity
GUT ISSUES Gut issues like constipation are one of the most common symptoms of GLP-1 due to the way it impacts the gastrointestinal system
Some doctors may prescribe Ozempic off-label (for a different purpose than its FDA approval) for weight loss
Most clinicians advise limiting it
The new data from the OASIS 4 trial of Novo Nordisk's 25 mg oral formulation of semaglutide included an indirect comparison between the drug and the STEP 1 trial of the current once-weekly injectable form of the GLP-1 agonist, branded as Wegovy
J Pediatr 1991, 118: 646-649
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