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Fatty acids that enter the mitochondria via CPT-1 are broken down into acetyl-CoA by -oxidation

Typically this means that the absorption rate is higher immediately after the dose is given and the rate then decreases as drug is absorbed

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Metformin lowers blood glucose by increasing peripheral uptake of glucose and decreasing hepatic glucose production, likely via inhibition of mitochondrial enzymes

Always consult a qualified healthcare provider before starting or changing any injection therapy