This process, known as glutathione conjugation, is catalysed by enzymes called glutathione S-transferases (GSTs)
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In contrast to NREM/SWS, Rapid Eye Movement sleep (REM), also known as Paradoxical Sleep (PS), has a core characteristic of muscle atonia with wake-like desynchronized EEG, cardiorespiratory irregularities, tremors, and episodic bursts of rapid eye movements
In addition, exposure to exogenous hydrogen peroxide can activate iron response elements involved in the regulation of iron metabolism by binding to mRNA, which can inhibit the translation of ferritin and reduce ferritin synthesis, thus increasing the concentration of free iron in cells
Glutathione is generally well-tolerated but can cause mild gastrointestinal side effects and, possibly, skin flushing
An increasing linear gradient of solvent B (v/v) was used as follows: 01 min, 2% B/D