Because prolonged opening of the BBB is associated with neuronal network dysfunction and long-term BBB dysfunction itself also indicates cortical damage, it is presumed that BBB damage in the epileptic brain contributes to epilepsy comorbidities
The cells were treated with 10 mM EtGSH in FluoroBrite DMEM for 34 h or vehicle (FluoroBrite DMEM)
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IV or high-dose oral glutathione may benefit neurological conditions like Parkinsons disease according to clinical protocols
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This process is modulated by several transporters, including aluminium-activated malate transporters (ALMTs), GABA transporters (GATs), bidirectional amino acid transporters (BATs), and cationic amino acid transporters (CATs)