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The finding that individuals with more pronounced external eating tendencies benefited more from this treatment suggests that its potential to alter unhealthy eating patterns before adverse health conditions develop warrants further exploration

GC-induced hyperglycemia has a multifactorial origin and can be explained by increased gluconeogenesis in the liver, inhibition of glucose uptake by adipose tissue, and changes in receptor and post-receptor functions [78]

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This observation is particularly important because it demonstrates that these drugs can remain effective even in the absence of the MC4R pathway, which is traditionally thought to play a key role in regulating energy balance and appetite

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However, there is little scientific evidence that proves GLP-1 patches are effective