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Complex I only directs superoxide toward the matrix, while complex III can direct O 2 .- toward the intermembrane space or the matrix (as demonstrated by using various agents that inhibit electron transport at different locations within complex III)

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812, pubmed.ncbi.nlm.nih.gov/26770075/

A growing body of evidence points to a relationship between glutathione levels and chronic illnesses such as fibromyalgia, myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and multiple chemical sensitivity (MCS)

While the term glutathione is often used broadly, not all supplements contain this active L form, which directly impacts absorption and efficacy

Biochim Biophys Acta 2013;1833:2996-3005