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One preclinical study (Valdecantos et al., ADA 2024) showed combination benefit in obese rats

HCG Injections: Stimulating Fat Loss While Preserving Muscle Human Chorionic Gonadotropin (HCG) is a hormone produced during pregnancy, and when used in weight loss treatments, it helps trigger the body to burn stored fat for energy

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Abdominal fat increases intra-abdominal pressure, forcing stomach contents upward against the lower esophageal sphincter

The study noted strongly stimulated dermal keratinocyte proliferation, indicating active tissue regeneration rather than merely surface effects

Now, we have to do some arithmetic