The increase in central neural activity is believed to be a consequence of an alteration in the normal balance between excitation and inhibition in nerve transmission, potentially due to a diminution of GABAergic inhibition 50,51,52
10.3389/falgy.2023.1236977 Summary Keywords pre-asthma, asthma, quality of life, asthma natural history, predisposition, risk factors Citation Scadding GK, McDonald M, Backer V, Scadding G, Bernal-Sprekelsen M, Conti DM, De Corso E, Diamant Z, Gray C, Hopkins C, Jesenak M, Johansen P, Kappen J, Mullol J, Price D, Quirce S, Reitsma S, Salmi S, Senior B, Thyssen JP, Wahn U and Hellings PW (2024) Pre-asthma: a useful concept for prevention and disease-modification
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Conflict of interest The authors have no conflict of interests related to this publication