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Trp53 negatively regulates autoimmunity via the STAT3-Th17 axis

Larbig, W., Gerber, W., Kluck, M., & Schoenenberger, G

Investigators are particularly interested in determining the mechanisms by which effects observed in murine models relate to broader mammalian metabolic regulation, and whether different experimental conditions (young vs aged models, healthy vs metabolically compromised states) show differential responses to NNMT inhibition

Several studies reported by Arreola et al

Amino acid transporters in cancer and their relevance to glutamine addiction: novel targets for the design of a new class of anticancer drugs