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This article provides essential information on taking these medications together, including safety considerations and practical guidance

Zinman B, Gerich J, Buse JB, et al, for the LEAD-4 Study Investigators

Furthermore, the liver participates in converting B12 into its active coenzyme forms: methylcobalamin and adenosylcobalamin

Changes in body composition (such as absolute reduction in fat-free body mass) are usually regarded as secondary outcomes, and in clinical practice, they may not be adequately matched with muscle-preserving support measures such as protein intake or resistance exercise

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