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Viability assay was also performed with combination of RSL3 and Fer1 (5 M) or ZVAD (50 M)

GSH is the most important antioxidant and free radical scavenger that is found to be decreased in the brains of people with a wide range of mental and neurological illnesses from schizophrenia[iv] to dementia[v] [vi]

Subsequently, cytochrome c staining was performed using the same method as that described for quantifying cytochrome c release using FACS analysis (Supplementary Data)

Freeman, J

Biochem Med (Zagreb) 2014

Although significant progress has been made in the research on the pathogenesis of neurodegenerative diseases such as Alzheimers disease, Parkinsons disease, amyotrophic lateral sclerosis and Huntingtons disease, and many drugs have found neuroprotective effects in cells and animal models, but there is still no drug that can produce clinical changes significantly in the pathogenesis