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Zhang XP, Hintze TH
Tirzepatide works on both GLP-1 and another hormone called glucose-dependent insulinotropic polypeptide (GIP)
Jardiance has shown reduction in cardiovascular mortality and heart failure hospitalisations in clinical trials
If you are finding one medication difficult to tolerate, switching is a clinical option worth discussing with your prescriber
Pins and needles (paraesthesia)
Because GLP-1s delay gastric emptying, they can increase residual gastric content raising the risk of pulmonary aspiration of gastric contents at induction and throughout an anesthetic even if a patient has been appropriately adherent to current NPO guidelines
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