These medications can affect kidney, liver, and blood-sugar function, so ongoing testing helps confirm that the treatment is both safe and working as intended
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Women using oral contraceptives should consider additional or alternative contraception for 4 weeks after initiating tirzepatide and following dose increases
Certain mood-related symptoms warrant prompt medical evaluation rather than self-management alone
Folinic acid (2 mg/kg/day, max 50 mg/day) produced significantly greater improvements in standardized verbal communication scores and several adaptive and behavioral subscales compared with placebo, with a stronger effect on children ( Furthermore, a placebo-controlled randomized trial evaluated the efficacy of folinic acid (5 mg twice daily) for 12 weeks in 19 children aged 310 years (sex distribution not reported) with ASD diagnosed by ADOS, without genetic syndromes, major medical comorbidities, or treatments affecting folate metabolism
3 Medications that should be avoided in patients with G6PD deficiency are listed in Table 3 , 6 and drugs that can be used safely in these patients are listed in Table 4
