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Oncogenic driver genes and the inflammatory microenvironment dictate liver tumor phenotype

Instead of relying primarily on historical relationships, many sponsors are exploring more data-driven approaches to site selection, including: regional disease heatmaps investigator performance analytics patient population modeling AI-assisted feasibility analysis These approaches aim to answer a fundamental question: Which sites can actually recruit the patients required for modern metabolic trials

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Multiple GLP-1R agonists have entered into clinical trials, with some, such as semaglutide, progressing to approval

Zhang L, Ludden CM, Cullen AJ, Tew KD, Branco de Barros AL, Townsend DM