semaglutide and pcos reddit My thoughts after 12 months on Wegovy (and a weight loss of 88 lbs) : r/ For my PCOS friends :

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GLP-1 GLP-1

B12 supplementation with semaglutide and B12 with tirzepatide are common pairings

Notably, over the subsequent 6 days, we observed a sustained body-weight-lowering effect after infusion of GLP-1MK-801, but not semaglutide, suggesting that the targeted inhibition of NMDA receptors in GLP-1 receptor-positive neurons might promote sustained changes to the defended level of adiposity

Since it's a substance your body naturally produces, it's generally very well-tolerated

Patients pay around $1,000 a month for treatment, and insurers are reluctant to pay