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Thus, SIRT1 can deacetylate LKB1 resulting in AMPK activation, closing a positive feedback loop between AMPK and SIRT1

The treatment of type 2 diabetes in the presence of renal impairment: what we should know about newer therapies

1046 Avocatin B, a natural CPT1 inhibitor from avocados, inhibits AML cell growth without harming normal hematopoietic stem cells, suggesting a potential new approach for blood cancer treatment

[PMID: 12804452] PubMed record related to this compound for laboratory literature review