No matter what you call it, this drug can be a powerful medicine or a serious health risk
Here, we focus on underexplored, metabolically driven PTMs that exemplify the direct cross-talk between metabolic reprogramming and immune signaling, including glycolysis-derived lactylation, tricarboxylic acid (TCA) cyclederived malonylation and succinylation, lipid metabolismderived palmitoylation and myristoylation, and amino acidderived modifications
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While ROS-induced oxidative stress can lead to cardiomyocyte death, recent research suggests that DOX degradation by oxyferrous myoglobin may actually reduce its cellular toxicity
K.SarkarO.MangrolaD.MathurP
The pGMBsub04 plasmid (ENA ID: LT622643) included the full B