Medical supply shortages have been sporadic occurrences since Covid disrupted supply lines, and they're only now settling down in time for tariff uncertainty to further disrupt them
First, start berberine at a low dose (typically 500 mg once or twice daily) and titrate slowly over 2-3 weeks while monitoring blood sugar, energy levels, and gastrointestinal symptoms
doi: 10.1080/10408360701713104 7 MerkoferMKissnerRHiderRCBrunkUTKoppenolWH
Moreover, macrocyclic ketones, steroids, and some peptides are the mainly active ingredients
Type 2 diabetes | Treatment summaries BNF NICE
Even for patients who have successfully lost weight on GLP-1 medications but then regain some of it after discontinuation, bariatric surgery may be an option to consider, especially if their BMI is back in the obese range