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To improve DE differentiation, the researchers incorporated PI3K inhibitor LY294002 (Ly) or CDK4/6 inhibitor PD into the small-molecule cocktails
Chen Y-M, Chang C-Y, Chen H-H, Hsieh C-W, Tang K-T, Yang M-C, et al
doi: 10.3892/IJMM.2025.5515 Summary Keywords glucagon-like peptide-1, type 2 diabetes, endothelial function, obesity, metabolic syndrome Citation Hammad BF, Zafar N, Ullah M, Faisal SJ, Iftikhar F, Waheed H, Muzaffar MW, Ahmed K, Ashraf F, Zahid K, Akhtar M and Mahmmoud Fadelallah Eljack M (2025) Exploring the multifaceted roles of GLP-1 receptor agonists
Beyond glycaemic control, they slash cardiovascular risk by up to 26%, reduce the progression of kidney disease, and treat fatty liver and sleep apnoea, among others
Any references to skin, collagen, extracellular matrix, or oxidative-stress pathways are provided only for research context and do not imply cosmetic or clinical use
Peptide therapy is not a replacement for surgery in all cases, but it can be an effective option for managing symptoms, supporting recovery, and in some cases helping patients delay or avoid surgical intervention.
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