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This review explores the biology of aging, the role of senescent cells in AD pathology, and various senotherapeutic approaches such as senolytics, dampening the SASP (senescence associated secretory phenotype), senescence pathway inhibition, vaccines, and prodrugs

Vitamin D deficiency is common

The fat loss raises natural testosterone while exogenous testosterone (if indicated) supports muscle preservation and energy during the weight loss phase

The BPC-157 peptide may work by stimulating growth factors to promote healing, but there is no evidence that it will cause muscle growth to improve body composition

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PMCID: PMC8069563