Insulin increases angiogenic and inflammatory mediators in retina The early worsening of DR has been consistently reported with the use of insulin and insulin secretagogues such as SUs and semaglutide [2,3,4,5, 9, 49], but not with insulin-independent antidiabetic agents like metformin or empagliflozin [6,7,8, 49]
Pickart noted that GHKs ability to change the pattern of gene expression helped support the idea that GHK may help slow or suppress cancer growth. A 2017 paper by Pickart et al
Potential side effects include GI upset, nausea and headache
Since these medications can affect appetite and food intake, they might lead to reduced intake of essential nutrients
Why Exercise on GLP-1s
Significantly upregulated mRNA expression of AKR1B1 (2.64-fold