If you are taking other glucose-lowering medications such as insulin or sulfonylureas, dose adjustments may be needed to prevent hypoglycemia
Similarly, exposure to methylglyoxal, a reactive dicarbonyl compound formed as a metabolic byproduct of glycolysis, has been shown to inhibit glycolysis, leading to a reduction in ATP and GSH concentrations
One morning youre standing in front of your fridge at 6 AM, pen in hand, ready for your weekly GLP-1 injection
GLP-1 receptor agonist medications like semaglutide have a half-life of approximately 7 days, meaning your body eliminates half of the active dose every week
For instance, an 8 mg weekly dose becomes two 4 mg injections
On December 20th, the FDA approved Eli Lillys Zepbound (tirzepatide) for the treatment of moderate-to-severe OSA in adults with obesity ( The SURMOUNT-OSA clinical trial assessed the efficacy of tirzepatide independently from CPAP therapy among a small subset of the total OSA population and does not compare the efficacy of tirzepatide to CPAP therapy in treating OSA