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For human xenograft studies, 2 10 6 HCT116 cells were transplanted 1:1 in Growth Factor Reduced Matrigel (Corning, CLS356231) into athymic nude mice (purchased from Inotiv), and the volume was calculated using the formula ( a b 2 )

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BPC157 exerts a significant protective effect on various tissues and organs, such as the esophagus, stomach, duodenum [2], colorectal mucosa [2], liver, pancreas [3], muscle [4], cornea [5], heart [6] and nerves [7]