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The UK medicines regulator, the MHRA, has updated the product information for healthcare professionals and patients regarding the "small risk of severe acute pancreatitis in patients taking GLP-1s." While rare, the sheer scale of GLP-1 use in the UK with one recent study suggesting 1.6 million adults had used them in the last 12 months, and 3.3 million were interested in trying them in the following year makes it important for clinicians and patients to be aware of the warning signs of pancreatitis, said the regulator

Here are five simple, realistic strategies that fit into any busy lifestyle: 1

Lactis, Bifidobacterium adolescentis, Lacticaseibacillus casei, Pediococcus acidilactici), plus Akkermansia (AKK) (Pasteurized Akkermansia muciniphila) (Akk11)

We would consider supplements such as methyl-folate and methyl B12, the active forms of B vitamins

It requires thoughtful oversight

This means you start with a low dose and slowly increase it over time