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Triple agonism is not simply "stronger" it engages a third hormonal lever that the other classes do not touch [3][4][9]

doi: 10.1038/nrdp.2018.14 135 CampbellJEDruckerDJ

JAMA Ophthalmol 134(12):13651372 Sharma N et al (2017) Comparison of oral Voriconazole versus oral Ketoconazole as an adjunct to topical Natamycin in severe fungal keratitis: a randomized controlled trial